Barry Honig is a biophysicist who specializes in bioinformatics and in developing theoretical methods for analyzing the physical chemical properties of macromolecules. He is particularly noted for innovating methods to compute and display the electrostatic potentials of macromolecules based on their 3D structures. The computer programs DelPhi and GRASP were developed in his laboratory and are widely used by the academic and industrial communities.

Since 1981, Dr. Honig has been a Professor of Biochemistry and Molecular Biophysics at Columbia University. In 1990, Dr. Honig was elected President of the Biophysical Society, he received an NIH Merit Award in 1995, and he is a recipient of the 2002 Founders Award of the Biophysical Society. Dr. Honig is a Howard Hughes Medical Institute (HHMI) Investigator. He serves on the editorial boards of several journals and has published over 190 scientific papers throughout his distinguished career.