Mark Murcko currently serves as an independent consultant to the biomedical community. Until November 2011 he was Vice President, Chief Technology Officer and Chair of the Scientific Advisory Board of Vertex Pharmaceuticals. Dr. Murcko is a co-inventor of Incivek™ (telaprevir), the world's most widely prescribed HCV protease inhibitor, as well as Agenerase™ (amprenavir) and Lexiva™ (fosamprenavir), Vertex's two marketed drugs for HIV. He is also a co-inventor of 8 other clinical candidates in the areas of cancer, inflammation/immunology, and infectious disease and was responsible for starting many of Vertex's programs in these and other disease areas. Prior to Vertex, Dr. Murcko worked at Merck Sharpe & Dohme, where he helped discover clinical candidates against cardiovascular and ocular diseases, including inhibitors of the enzyme carbonic anhydrase for the treatment of glaucoma. One of Merck's development candidates in this area, Trusopt™ (dorzolamide), became the first marketed drug in pharmaceutical history to result from a structure-based drug design program. Dr. Murcko is highly regarded as an innovator and champion of disruptive technologies. He has served on the editorial boards of many scientific publications, including the Journal of Medicinal Chemistry and Drug Discovery Today, and will serve as the Chair of the 2013 Gordon Research Conference in Medicinal Chemistry. He is a co-inventor on more than 40 issued patents and has co-authored more than 85 scientific articles.