The Schrödinger Boston User Meeting will be held at the Museum of Science on June 6-7, preceding the Structure-Based Drug Design conference.

As in past years, the Regional User Meetings offer a great opportunity to see current research from your colleagues and to learn about the latest developments from Schrödinger. This year's meeting will include an introduction to Suite 2011, user presentations, and hands-on workshops. The Boston meeting is two days and will involve more talks and workshops than the other venues.

Agenda

Monday, June 6
 1:00 pm   BioLuminate: A Preview of the Schrödinger Structure-Based Biologics Product
                    Dave Pearlman, BioLuminate Product Manager, Schrödinger
 1:40 pm   Protein–Protein Docking: Is the Glass Half Full or Half Empty?
                    Sandor Vajda, Professor, Biomedical Engineering, Boston University
 2:30 pm    Coffee Break
 3:00 pm   Free Energy Perturbation Applications to Ligand Selectivity, Potency, and  
                   Effects of Mutations on Protein Structure
                    Soumya Ray, Assistant Professor of Neurology, Brigham and Women's Hospital
 3:40 pm   What is New in Suite 2011
                    Woody Sherman, Vice President of Applications Science, Schrödinger
 4:30 pm    Suite 2011 Demo
 5:00 pm    Reception at Schrödinger Office

Tuesday, June 7
  9:30 am   Small, Covalent Peptidomimetic Inhibitors of CRM1 Mediated Nuclear
                     Transport
                      Sharon Shechter, Head of Computational Discovery, Karyopharm
10:10 am   Structure of Human O-GlcNAc Transferase-Substrate Complex and Insights
                     from Molecular Dynamics and Docking
                      Piotr Sliz, Assistant Professor, Harvard Medical School
10:50 am    Coffee Break
11:20 am   Core Hopping and R-Group Analysis
                     Peter Shenkin, Core Hopping Product Manager, Schrödinger
12:00 pm   PyMOL: New Features and Demo
                     Jason Vertrees, PyMOL Product Manager, Schrödinger
12:30 pm    Lunch
  1:30 pm   How Molecular Dynamics Simulation May be Applied in Structural Based
                    Design of Kinase Drugs
                      Yibing Shan, Senior Scientist, D.E. Shaw Research
  2:10 pm   Pathway and Mechanism of Drug Binding to G Protein-Coupled Receptors
                      Albert Pan, Research Scientist, D.E. Shaw Research
  2:40 pm    Coffee Break
  3:10 pm   Metadynamics: Applications to Conformational Analysis of Biologically and
                    Pharmaceutically Relevant Systems
                      Dima Lupyan, Senior Scientist, Schrödinger
  3:50 pm   A Brief Introduction to Seurat
                      James Baxendale, Vice President of Enterprise Informatics &
                      Seurat Product Manager, Schrödinger
  4:00 pm    Training, Demonstrations, and Discussion
                     -PyMOL with Jason Vertrees
                     -Seurat with James Baxendale
                     -R-group Analysis with Peter Shenkin
                     -Multiple Sequence Viewer with Piotr Rotkiewicz
                     -Maestro Elements with Kathryn Loving
                     -Maestro with Woody Sherman
                     -The Role of MD in Drug Discovery with Dima Lupyan, Albert Pan,
                      and Yibing Shan

Registration

This meeting is offered free of charge, but we ask that you register to reserve your space. To register, please submit this short online form.