5th European Life Science Bootcamp

March 20, 2017 to March 23, 2017

We’re pleased to announce Schrödinger's 5th European Life Science Bootcamp - a series of interactive live webinars that will cover a wide range of topics. Each webinar will include 10 minutes of presentation, 20 minutes of software demonstration, followed by live Q&A.

You can register for individual sessions by using the links below or the entire series by clicking here. We hope you’ll take this opportunity to join us!

DateTimePresentationRegister
Monday, Mar. 20th14.00 CET

Watermap for Lead Optimisation
presented by Daniel Robinson

WaterMap was previously introduced in our 3rd European Bootcamp. If you would like a reminder of how to better understand waters in your protein-ligand systems, this is another introductory session covering:

  • What is a WaterMap? 
  • How do I interpret results of a WaterMap? 
  • Examples of solvation effects on SAR
Click Here
Tuesday, Mar. 21st11.00 CETIntroduction and Case Studies in Free Energy Perturbation for Lead Optimisation
presented by Thomas Steinbrecher

FEP was previously introduced in our 3rd Bootcamp. If you would like a reminder plus learn the latest, then we will cover both the background of this powerful technique for modelling binding affinity, and, look over recent method improvements and case studies.
  • FEP+ background and theory 
  • Core-hopping, HMR and other recent improvements 
  • Case Studies
Click Here
Wednesday, Mar. 22nd11.00 CETBecoming an Expert in PyMOL: Customization and Scripting
presented by Daniel Cappel

Learn how to improve your PyMOL skills, for:
  • Managing selections 
  • Running scripts 
  • Customizations 
  • Creating your own scripts
Click Here
Wednesday, Mar. 22nd15.00 CETModelling Peptide Binding: From Structure to Properties
presented by Jianxin Duan

In this session, we will discuss various approaches to understanding peptide-protein interactions. We will cover modelling in both 3D and 2D space, discussing:
  • Peptide docking
  • Peptide mutations
  • Managing non-natural amino acids
  • Peptide QSAR
Click Here
Thursday, Mar. 23rd11.00 CET

Using Phase for Pharmacophore Modelling
presented by Katalin Phimister

New Phase for pharmacophore modelling was previously introduced in our 4th Bootcamp. Here is a reminder for how to generate pharmacophores both from ligands and protein structures. We will cover:

  • Feature definitions 
  • Validation tools 
  • An application example
Click Here
Lead Optimization, Target Validation and Structural Enablement