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When I quit Maestro, I see error messages in the startup window like error removing /home/auser/.schrodinger/tmp/46503: /home/auser/.schrodinger/tmp/46503/.nfs0000000000d5357e00000066: Device or resource busy Are these serious?

No. They occur during cleanup when some temporary files used by Maestro are stored on a network-mounted file system, and do not affect the closing down of Maestro.

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