Training
Biologics Drug Discovery
Software Release
Topic
Type
Product
FEP+ for Biologics.
Antibody Humanization Guided by Computational Modeling
New Approaches for Modeling Protein Aggregation and Solvation
Chemical Degradation in Therapeutic Proteins: Insights from Microsecond Molecular Dynamics and QM Calculations
Protein Engineering Guided by Physics-based Computational Modeling
A common and significant goal in the design and optimization of biologic drugs is the reliable prediction of the impact...
Leveraging Molecular Modeling in the Selection of Protein-Drug Candidates for Late-Stage Developability
A Reassessment of the Thermodynamic Forces that Stabilize Folded Protein Conformations in Aqueous Solutions
Biologics by Design
Biologics are one of the most important classes of therapeutics, despite this, application of rational design...
Structure-based Anti-viral Design using Schrödinger's Biologics Modeling Suite
Multiscaling the CRISPR-Cas Revolution from Genome Editing to Viral Detection
Multiscale Modelling of DNA Compaction
Multiscale Modelling of Chromatin Liquid-liquid Phase Separation
Improving the Stability of RNA Therapeutics through Biophysics, Machine Learning, and Crowdsourcing
Models for Liquid-liquid Phase Separation of Intrinsically Disordered Proteins
When can Simplified Models be used for Describing Protein Solution Behaviour?
Structure-based Anti-Viral Design using Schrödinger’s Biologics Modeling Suite - Chinese
Since prehistoric time, virus infection has been a threat to human health. Modulation of immune response is one of the...
Molecular Simulations of Nascent Lipid Droplets
Computational Workflows for Bifunctional Degrader Design
Specific proteins within cells can be targeted for degradation by ubiquitin‐protease systems using bifunctional small...
Design and Optimization of Biologics Driven by Physics-Based Computational Modeling
In this webinar, we will address the important role that computational modeling can play in accelerating the discovery...
Case Study - Hit Finding using the Schrödinger Platform
A Molecular-Level Examination of Amorphous Solid Dispersion Formulation Dissolution
Digitalization of Pharma Research: Holistic Approaches and Their Impact on Drug Discovery Projects
Exploring Enumerated Libraries through Largescale Free Energy Perturbations