Training

Biologics Drug Discovery

Clear Filters

Software Release

Topic

Type

Product

Search Documentation

Getting Started: Get to Know Maestro BioLuminate

BioLuminate is a graphical user interface that serves as the gateway to structure-based modeling for biologics. The user-friendly interface presents a set of robust physics-based solutions for the discovery and development of a wide array of biologic products ranging from peptides, enzymes and nucleic acids to monoclonal antibodies and various forms of therapeutic proteins. BioLuminate includes dedicated sequence analysis and visualization capabilities consolidated in its accompanying Multiple Sequence Viewer.

Multiple Sequence Viewer
All of the resources and training material you need to get to know about BioLuminate’s sequence analysis, visualization and editing capabilities.
Training Collection View
Maestro BioLuminate Quick Reference Card
Get started with the Maestro BioLuminate Quick Reference Card.
Quick Reference Card View
Getting Going with Maestro BioLuminate
A free video series introducing the basics of using Maestro BioLuminate.

Video Series View

Tutorials

Self-guided step-by-step introductions to various workflows with example files for getting comfortable with Schrödinger tools.

Introduction to BioLuminate and the Multiple Sequence Viewer/Editor
Prepare and visualize an enzyme, analyze the sequence for residue conservation, and build a homology model with the MSV.
Tutorial View
Antibody Visualization and Modeling in BioLuminate
Visualize, build, and evaluate antibody models, analyze an antibody for various characteristics, dock an antigen to an...
Tutorial View
Batch Homology Modeling Using the Multiple Sequence Viewer/Editor
Build multiple homology models using a single template with the MSV.
Tutorial View
Building Homology Models with the Multiple Sequence Viewer/Editor
Build and refine a homology model with the MSV.
Tutorial View
Heteromultimer Homology Modeling with the Multiple Sequence Viewer/Editor
Build a heteromultimer homology model of human hemoglobin from a bar-head goose hemoglobin structure.
Tutorial View
Sequence Annotation of Antibodies with the Multiple Sequence Viewer/Editor
Annotate an antibody sequence with residue-level properties with the Multiple Sequence Viewer/Editor (MSV).
Tutorial View
View More

Online Courses

A range of courses—from beginner (people new to computational tools) to advanced (experienced modelers who are learning the Schrödinger platform)—that integrate videos, tutorials, and hands-on training resources.

Introduction to Computational Antibody Engineering
Learn molecular modeling solutions for antibody discovery and design.
Online Course View

Webinars

Recordings of past online events and presentations. These are typically 30 - 60 minutes long and cover more complex topics and workflows.

Optimizing Protein Stability Using New Computational Design Approaches for Biologics
Physical stability is a key determinant of the clinical and commercial success of biological therapeutics, vaccines,...
Webinar View
Antibody Modeling with the Schrödinger Platform
This webinar presents the tools available in BioLuminate to model antibody structures, covering homology modeling,...
Webinar View
Modelling Peptide Binding: From Structure to Properties
In this session we will discuss various approaches to understanding peptide-protein interactions. We will cover...
Webinar View
Biologics - Modeling with BioLuminate
Preparing a protein structure for modeling Evaluating the quality of a structure Assessing liabilities with the Protein...
Webinar View
Using Structure-Based Modeling to Address Liabilities in Biologics
Antibodies have emerged as a key therapeutic scaffold in drug discovery. This is largely tied to very mature and...
Webinar View
Aggregation Scoring and Liability Prediction using Schrödinger's Biologics Suite
Antibodies are a key therapeutic scaffold in drug discovery. This is largely tied to very mature and efficient...
Webinar View
View More

Videos

Short video overviews of specific introductory and scientific topics, including summaries of new release features.

Setting up a BioLuminate Project
The first video in the Getting Going with Maestro BioLuminate Video Series: changing your working directory, saving projects, and more.
Video View
Importing and Rendering Structures in BioLuminate
The second video in the Getting Going with Maestro BioLuminate Video Series: importing structures from the Protein Data Bank (PDB), selection and inclusion and...
Video View
Interacting with Objects and Applications in BioLuminate
The third video in the Getting Going with Maestro BioLuminate Video Series: ways to use right-clicks in BioLuminate, managing surfaces.
Video View
Interacting with and Favoriting Applications in BioLuminate
The fourth video in the Getting Going with Maestro BioLuminate Video Series: favorites toolbar, navigating the Tasks menu.
Video View
Introduction to Workspace Toggles and the Structure Hierarchy in BioLuminate
The fifth video in the Getting Going with Maestro BioLuminate Video Series: workspace toggles, the Structure Hierarchy, Adding Antibody Annotations to the...
Video View
A Sneak Peek into Renumbering Residues and the Project Table in BioLuminate
The sixth video in the Getting Going with Maestro BioLuminate Video Series: renaming chains and residues, the Project Table.
Video View
View More

Quick Reference Sheets

A one-page PDF that visually describes the panel or workflow.

2D Sketcher
Quick Reference Sheet View
Using the Command Line with Schrodinger Platform Cheat Sheet
Quick Reference Sheet View
Protein Preparation Workflow
Quick Reference Sheet View
Back To Top