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What’s new in the Life Science Schrödinger Suite Release 2025-2

We release new platform usability and technological improvements quarterly.

  • New Crystal Structure Prediction interface to rank Z’=1 crystal polymorphs with high fidelity
  • New FEP+ Pose Builder workflow to automatically generate high-quality ligand alignments (Beta)
  • Faster ligand scoring and docking with optimized Glide (Beta)
  • Expanded support for protein degrader modeling with the new Degrader Sampling Workflow (Beta)
  • Augmented AI/ML capabilities for biologics with machine learning-based T-cell receptor (TCR) structure prediction (Beta)
Release notes

What’s new in the Materials Science Schrödinger Suite Release 2025-2

We release new platform usability and technological improvements quarterly.

  • Automated Formulation ML solution for optimization of formulations
  • OLED Device ML for high-throughput design and optimization of device performance
  • New Crystal Structure Prediction interface to rank Z’=1 crystal polymorphs with high fidelity
  • Improved reactive adsorption and desorption analysis with new MS Surface solution
  • Accelerated conformational search with CREST
Release notes

Interested in downloading PyMOL?

PyMOL is a user-sponsored molecular visualization system on an open-source foundation, maintained and distributed by Schrödinger.

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System Requirements

View all system requirements for Linux, Windows, Mac installations and supported GPU hardware.