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PyMOL is a user-sponsored molecular visualization system on an open-source foundation, maintained and distributed by Schrödinger.

Life-Science-Loop-Release-2024-3

What’s new in the Life Science Schrödinger Suite Release 2024-3

We release new platform usability and technological improvements quarterly.

  • Full release of the OPLS5 polarizable small molecule force field
  • New Lambda Dynamics-enhanced protein residue mutation FEP+ to rapidly identify high quality protein variants (Beta)
  • New Unbinding Kinetics workflow in Desmond for gaining insights into drug-target residence time (Beta)
  • Expanded DNA/RNA modeling toolkit
Release notes
Materials-Science-Loop-Release-2024-3

What’s new in the Materials Science Schrödinger Suite Release 2024-3

We release new platform usability and technological improvements quarterly.

  • Automated parametrization for coarse-grained simulations
  • Machine learning prediction for water solubility
  • Singlet-exciton energy transfer (SEET) predictions
  • Improvements to machine learning for materials formulations
  • New implicit solvation model for quantum chemistry
  • New histogram in MS Maestro
Release notes
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System Requirements

View all system requirements for Linux, Windows, Mac installations and supported GPU hardware.