What’s new in the Life Science Schrödinger Suite Release 2025-4
We release new platform usability and technological improvements quarterly.
- Accurately generate, score, and optimize your protein degrader complexes with structure-based in silico workflows (Beta)
- Enable precise, efficient TCR modeling through a full stack of proven in silico methods
- Addition of immiscible probes in Mixed Solvent MD to better identify cryptic pockets
- Expansion of drug formulations applicability with highly accurate Z’=2 polymorph predictions (Beta)
What’s new in the Materials Science Schrödinger Suite Release 2025-4
We release new platform usability and technological improvements quarterly.
- Automated mapping for coarse-grained protein models
- Model building solution for complex bilayers
- Predictive solution for ionic conductivity
- Expanded support for machine learning force fields (MLFF)
- Support for Universal Models for Atoms (UMA)
Interested in downloading PyMOL?
PyMOL is a user-sponsored molecular visualization system on an open-source foundation, maintained and distributed by Schrödinger.

System Requirements
View all system requirements for Linux, Windows, Mac installations and supported GPU hardware.