Opening new worlds for molecular discovery
Schrödinger’s computational platform, powered by physics, is transforming the way therapeutics and materials are discovered to make innovations of the future achievable, today.
Leverage the power of our industry-leading platform to discover and optimize better molecules, faster.
Discover, optimize, and formulate the materials of the future with our predictive computational platform.
Schrödinger’s therapeutics group strives to reduce risk in drug discovery and development by selecting high-value targets with established human genetics or clinical validation, where we can solve a design challenge, and where we believe we can deliver value for patients.
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In this webinar, Schrödinger’s medicinal and computational chemists will show how they tackled the EGFR triple-mutant problem by coupling industry-leading free energy perturbation technology (FEP+) with de novo design workflows to effectively explore novel chemical space and identify reversible inhibitor scaffolds.