BioLuminate
Comprehensive modeling platform for biologics discovery
Unlock the possibilities of biologics design
Maestro BioLuminate is Schrödinger’s comprehensive interface to streamline computationally-guided biologics drug discovery. By leveraging industry-leading molecular simulations and logically organizing tasks and workflows, BioLuminate provides predictive methods to optimize properties of biomolecules from sequence to structure.
Design better quality biomolecules with a comprehensive, user-friendly platform
Build & Model
- Easily build accurate structural models which serve as key starting points for rational design of biologics
- Model antibody structures using a fully guided, specialized workflow incorporating de novo CDR loop sampling
- Leverage advanced protein sequence analysis tools, including annotation capabilities
Predict & Analyze
- Access cutting-edge, predictive computational modeling workflows for biologics discovery within a streamlined portal
- Predict and analyze protein-protein or protein-nucleic acid interactions at the atomic level using computational workflows
- Calculate descriptors for characterizing and triaging antibodies and proteins, including protein surface properties and aggregation propensity
Design & Engineer
- Enumerate potential amino acid substitutions and design focused libraries
- Perform in silico mutagenesis to engineer novel variants with superior binding affinity, selectivity, and thermostability
- Design flexible linkers and rigid linkers to generate multi-functional fusion proteins
Broad application across protein-based therapeutics discovery
Access refined workflows across multiple biological modalities
Featured Course
Learn how to use BioLuminate for antibody engineering with our hands-on, online certification course
Level-up your computational modeling skills and enroll in our online course, Introduction to Computational Antibody Engineering.
view courseWebinars
Discover how Schrödinger technology is being used to solve real-world research challenges.
Design and optimization of biologics driven by physics-based computational modeling
Antibody modeling with the Schrödinger platform
Enzymes by design: Structure-based methods for modeling enzymes
Publications
Browse the list of peer-reviewed publications using Schrödinger technology in related application areas.
Training & Resources
Online certification courses
Level up your skill set with hands-on, online molecular modeling courses. These self-paced courses cover a range of scientific topics and include access to Schrödinger software and support.
Tutorials
Learn how to deploy the technology and best practices of Schrödinger software for your project success. Find training resources, tutorials, quick start guides, videos, and more.
Other Resources