Webinar
Life Science
- Feb 5, 2025
Next-generation protein engineering with physics: Predicting affinity, stability, selectivity, and pH-dependent binding
In this webinar, we will introduce Schrödinger’s FEP+ Residue Scan, a next-generation tool that achieves approximately 15x speedup compared to traditional Protein FEP methods, without significant loss of accuracy.
Webinar
Life Science
- Jan 16, 2025
Schrödinger デジタル創薬セミナー: Into the Clinic ~計算化学がもたらす創薬プロセスの変貌~ 第15回
Water matters: Enhancing early drug discovery with insights from water energetics
Webinar
Life Science
- Dec 18, 2024
アーカイブ配信: OPLS5及び解離速度定数の予測技術のご紹介
DEC 18, 2024 | 本ウェビナーではOPLS5とunbinding kinetics workflowに焦点を当ててご紹介します。
Webinar
Life Science
- Nov 20, 2024
Water matters: Enhancing early drug discovery with insights from water energetics
In this webinar, we discuss the impact of two technologies that leverage explicit water energetics in the binding pocket to enhance drug design—WaterMap and Glide WS.
Webinar
Life Science
- Nov 19, 2024
Schrödinger デジタル創薬セミナー: Into the Clinic ~計算化学がもたらす創薬プロセスの変貌~ 第14回
Advancements in machine learning enhanced in silico design: Impact on a pipeline of drug discovery programs
Webinar
Life Science
- Nov 13, 2024
アーカイブ配信: E-sol to Predict Unbound Brain-to-Plasma Partition Coefficient, Kp,uu
NOV 13, 2024 |本ウェビナーでは、E-solの基本から応用事例、FAQまでを解説し、創薬研究におけるE-sol活用の可能性を探ります。
Webinar
Life Science
- Nov 7, 2024
Innovations in Protein Modeling: How Physics is Impacting Industrial Drug Discovery
In this webinar, hear from The Protein Society and invited speakers from Schrödinger, UCB, and Nested Therapeutics as they discuss three real-life drug discovery case studies that were impacted by the use of physics-based molecular simulations.
Webinar
Life Science
Materials Science
- Nov 6, 2024
Computationally-Guided Drug Formulation Webinar Series
In this webinar series, we explore how the latest computational modeling tools are impacting the various steps in the pharmaceutical formulation process.
Webinar
Life Science
Materials Science
- Nov 6, 2024
Modeling lipid nanoparticles: Self-assembly and apparent pKa calculation
In this webinar, we introduce Schrödinger’s coarse-grained simulation technology that can simulate the formation of LNP structures from a random mixture.
Webinar
Life Science
Materials Science
- Oct 23, 2024
Crystal structure prediction workflow for small molecule drug formulation
In this webinar, we describe how early assessment of crystal polymorphism and thermodynamic solubility continues to be elusive for drug discovery and development despite its critical importance, especially for the ever-increasing fraction of poorly soluble drug candidates.
Webinar
Life Science
- Oct 17, 2024
Schrödinger デジタル創薬セミナー: Into the Clinic~計算化学がもたらす創薬プロセスの変貌~第13回
OCT 17, 2024 | Broadly Impacting Biologics Discovery via Physics-Based Modeling: Antibody Affinity, pH-Sensing and More
Webinar
Life Science
- Oct 15, 2024
Schrödinger Software 2024-3 新機能紹介ウェビナーアーカイブ配信
SEPT 3, 2024 | この度、最新版となる2024-3をリリースいたしました。本ウェビナーでは、主要な新機能についてご紹介いたします。
Case Studies
Case Study
Life Science
Case Study
Life Science
Case Study
Life Science
Events
Event
Materials Science
- Jan 29th-31st, 2025
【1月29日(水)～31日(金)】nano tech 2025 出展
展示ブースでは、セミナー開催のほか、先進の技術について専門技術者が解説し、お客様からのご質問にお答えします。 小間番号：4M-10 出展ゾーン：材料：Materialゾーン
Webinar
Life Science
- Feb 5, 2025
Next-generation protein engineering with physics: Predicting affinity, stability, selectivity, and pH-dependent binding
In this webinar, we will introduce Schrödinger’s FEP+ Residue Scan, a next-generation tool that achieves approximately 15x speedup compared to traditional Protein FEP methods, without significant loss of accuracy.
Event
Materials Science
- Feb 9th-13th, 2025
The 29th Biennial ORCS Meeting
Schrödinger is excited to be participating in The 29th Biennial ORCS Meeting taking place on February 9th – 13th in Myrtle Beach, South Carolina.
Product Videos
Video
Life Science
- Nov 27, 2023
Getting Going with Maestro BioLuminate
A free video series introducing the basics of using Maestro Bioluminate.
Video
Life Science
- Nov 27, 2023
Getting Going with Maestro
A free video series introducing the basics of using Maestro.
Video
Life Science
- Nov 20, 2023
A Sneak Peek into Renumbering Residues and the Project Table in BioLuminate
The sixth video in the Getting Going with Maestro BioLuminate Video Series: renaming chains and residues, the Project Table.
Publications
- Publication
- Dec 22, 2024
Structure-based discovery and development of highly potent dihydroorotate dehydrogenase inhibitors for malaria chemoprevention
Nie Z, et al. J. Med. Chem., 2025, 68, 1, 590–637- Publication
- Dec 16, 2024
Leveraging the thermodynamics of protein conformations in drug discovery
Zhang BW, et al. J. Chem. Inf. Model., 2024- Publication
- Dec 13, 2024
In silico enabled discovery of KAI-11101, a preclinical DLK inhibitor for the treatment of neurodegenerative disease and neuronal injury
Lagiakos H.R., et al. J. Med. Chem., 2024Quick Reference Sheets
Tutorials
- Tutorial
- Feb 2, 2024
Introduction to MD Simulations with Desmond
Prepare, run, and perform simple analysis on an all-atom MD simulation with Desmond.
- Tutorial
- Jan 30, 2024
Designing Out Common ADMET Liabilities using Consensus IFD-MD
Use Consensus IFD-MD to generate a model that can be used to improve selecitvity between an on-target protein and hERG
- Tutorial
- Jan 30, 2024
Ligand-based Screening for Ultra-Large Libraries with Quick Shape and the Hit Analyzer
Perform a Quick Shape screening on a library of 20000 compounds and analyze the results.
Webinars
Webinar
Life Science
- Feb 5, 2025
Next-generation protein engineering with physics: Predicting affinity, stability, selectivity, and pH-dependent binding
In this webinar, we will introduce Schrödinger’s FEP+ Residue Scan, a next-generation tool that achieves approximately 15x speedup compared to traditional Protein FEP methods, without significant loss of accuracy.
Webinar
Life Science
- Jan 16, 2025
Schrödinger デジタル創薬セミナー: Into the Clinic ~計算化学がもたらす創薬プロセスの変貌~ 第15回
Water matters: Enhancing early drug discovery with insights from water energetics
Webinar
Life Science
- Dec 18, 2024
アーカイブ配信: OPLS5及び解離速度定数の予測技術のご紹介
DEC 18, 2024 | 本ウェビナーではOPLS5とunbinding kinetics workflowに焦点を当ててご紹介します。
White Papers
White Paper
Life Science
- Oct 29, 2024
20 Years of Glide: A Legacy of Docking Innovation and the Next Frontier with Glide WS
Glide has long set the gold standard for commercial molecular docking software due to its robust performance in both binding mode prediction and empirical scoring tasks, ease of use, and tight integration with Schrödinger’s Maestro interface and molecular discovery workflows.
White Paper
Life Science
White Paper
Life Science
Latest insights from Extrapolations blog
With FEP+, “The Experiment is the Limit.”
Over the past century, small molecule drugs have represented the dominant modality in drug research, enabling medical breakthroughs that have saved countless lives.
Tackling Drug Solubility: AbbVie and Schrödinger Collaborate to Advance Accurate Prediction Methods
The complexity and size of drug candidates has grown in recent years as scientists pursue novel targets once considered undruggable.
Blog
Can AlphaFold Models be Used for Structure-Based Drug Design? A Perspective Two Years In
We recently sat down with Edward Miller, Senior Director of Protein Structure Modeling at Schrödinger, to discuss his experience using AlphaFold models for SBDD.
Training & Resources
Online certification courses
Level up your skill set with hands-on, online molecular modeling courses. These self-paced courses cover a range of scientific topics and include access to Schrödinger software and support.
Free learning resources
Learn how to deploy the technology and best practices of Schrödinger software for your project success. Find training resources, tutorials, quick start guides, videos, and more.
Other Resources