Glide
Industry-leading ligand-receptor docking solution
Amplify your ligand discovery with an accurate, versatile docking program
Glide is the leading industrial solution for reliable ligand-receptor docking. It augments and accelerates structure-based drug design across a range of applications, including virtual screening, binding mode prediction and interactive 3D molecular design.
Advantages of Glide for ligand-receptor docking
Easy-to-use graphical interface
Easily create and validate docking models with a simple, guided graphical user interface
High docking accuracy across diverse receptor types
Achieve high enrichment across a diverse range of receptor types, including small molecules, peptides, and macrocycles
Customizable constraints
Benefit from a broad range of constraints to easily bias docking calculations to meet experimentally-observed requirements and desired chemical space
Save compute time and effort using prepared commercial libraries for Glide
Schrödinger has partnered with leading providers to help you access commercial databases of fragments, lead-like, near drug-like, and drug-like compounds ranging from millions to billions of compounds encompassing a vast chemical space.
Powerful use cases across drug discovery
Interactive 3D design
Interactively design and dock in 3D using goal-directed ligand design workflows in Ligand Designer and LiveDesign
Virtual screening
Perform virtual screens with automated workflows that are customizable to fit project needs
Ultra-large scale virtual screening
Accelerate screening of ultra-large libraries (>1B compounds) using Glide accelerated by Active Learning
Covalent docking & scoring
Dock a set of ligands that bind covalently to the receptor, using predefined or custom reaction chemistry — CovDock
Featured
Dramatically improving hit rates with a modern virtual screening workflow
See how Active Learning Glide and ABFEP+ (Absolute Binding FEP+) are revolutionizing hit discovery in a modern virtual screening workflow to identify better quality hits, faster.
Read the white paper
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Publications
Browse the list of peer-reviewed publications using Schrödinger technology in related application areas.
Training & Resources
Online certification courses
Level up your skill set with hands-on, online molecular modeling courses. These self-paced courses cover a range of scientific topics and include access to Schrödinger software and support.
Tutorials
Learn how to deploy the technology and best practices of Schrödinger software for your project success. Find training resources, tutorials, quick start guides, videos, and more.
Other Resources