Training
Biologics Drug Discovery
Software Release
Topic
Type
Product
Optimizing Protein Stability Using New Computational Design Approaches for Biologics
Physical stability is a key determinant of the clinical and commercial success of biological therapeutics, vaccines,...
Antibody Modeling with the Schrödinger Platform
This webinar presents the tools available in BioLuminate to model antibody structures, covering homology modeling,...
Modelling Peptide Binding: From Structure to Properties
In this session we will discuss various approaches to understanding peptide-protein interactions. We will cover...
Biologics - Modeling with BioLuminate
Preparing a protein structure for modeling Evaluating the quality of a structure Assessing liabilities with the Protein...
Using Structure-Based Modeling to Address Liabilities in Biologics
Antibodies have emerged as a key therapeutic scaffold in drug discovery. This is largely tied to very mature and...
Aggregation Scoring and Liability Prediction using Schrödinger's Biologics Suite
Antibodies are a key therapeutic scaffold in drug discovery. This is largely tied to very mature and efficient...
Homology Modeling with the Schrödinger Biologics Suite
Homology modeling can expand the domain of applicability of structure-based tools, making them available to study...
Protein FEP: Free Energy Perturbation on Protein Residues with the Schrödinger Platform
In recent years, the Schrödinger Free Energy Perturbation tool (FEP+) has been used to accurately predict the relative...
What Biologics Modelling Can Do For You
Protein-based drugs are one of the most important classes of therapeutics nowadays. Despite this, the field of rational...
Structure-based Vaccine Design using Schrödinger’s Biologics Modeling Suite
The science of vaccine development has made remarkable progress in the last two decades. Originally, vaccine design was...
Structure-based Anti-Viral Design using Schrödinger’s Biologics Modeling Suite
Since prehistoric time, virus infection has been a threat to human health. Modulation of immune response is one of the...
What Can Biologics Modelling Do For You?
Protein-based drugs are one of the most important classes of therapeutics. Despite this, the field of rational design...
Structure-based Anti-Viral Design using Schrödinger’s Biologics Modeling Suite
Since prehistoric time, virus infection has been a threat to human health. Modulation of immune response is one of the...
Design and Optimization of Biologics Using Structure-Guided Computational Modeling
Accurate and reliable computational solutions for designing and optimizing biologics can play an effective role in...
Accurate Prediction of Protein Thermostability using FEP+
Accurately predicting the protein thermostability changes upon single point mutations in silico is a challenge that has...
Enzymes by Design: Structure-based Methods for Modeling Enzymes
An overview of how the Schrödinger technology can be used to optimize enzymes using structure-based rational design.
Computational Approaches to Protein Aggregation Propensity Prediction
Antibodies are key molecules in biotherapeutics drug discovery due to their modular composition and their prominent...
Panel Discussion - What Impact Does Computational Modeling have in Biologics
Join Schrödinger's Biologics experts for a discussion on computational modeling and its role in Biologics.
Rational Design of Peptides: Leveraging Structural Data and Computer-aided Methods
Developing peptide therapeutics can really benefit from structural information about the peptide and the peptide-target...
Calculating Viscosities of Concentrated Protein Solutions
Rationale and applications of multi-scale modeling of protein solutions will be described with an emphasis on the...
Effect of Ion Binding and Ion Exclusion on Biomolecular Interactions: Multiscale Simulations of Crowded Protein Solutions
Coarse-Grained Molecular Models for Predicting Electrostatic Protein Self-Interactions and the Role of Multi-Residue Interactions
Molecular Association on Surface with Widely Varied Properties: Insights from DNA Biosensor and Amyloid Peptide Aggregation