Bio-IT World 2025
- April 2nd-4th, 2025
- Boston, Massachusetts
Schrödinger is excited to be participating in the Bio-IT World conference taking place on April 2nd – 4th in Boston, Massachusetts. Join us for a poster presentation by Hansen Han, Developer II at Schrödinger, titled “BioInsight, a customized application for biomarker exploration and discovery.” Stop by booth 509 to speak with Schrödinger scientists.
Poster: BioInsight, a customized application for biomarker exploration and discovery
Presenter:
Hansen Han, Developer II, Schrödinger
Introduction:
Cell lines and other preclinical models are routinely used for drug screening studies. Genomic profiles are largely available for these models. Genomic features derived from multi-omic profiles are often associated with the screening results to identify therapeutic biomarkers. These features include gene-level genomic data related to gene expression, mutation, copy number, protein expression, and gene dependency. There is also a growing body of knowledge on composite genomic features that could serve as candidate biomarkers. These include pathway activities, gene signatures, tumor mutation burden (TMB), chromosomal instability (CIN) status, MSI status, tumor subtypes. Although information on these genomic features are available in public portals or in publications, there is currently no central repository that integrates these genomic features with pharmacogenomic screening studies across model types or internal and external resources, making it challenging to explore and discover biomarkers in a comprehensive and unified manner.
Panel Discussion: Demystifying AI—Real Examples in Drug Development
Panelist:
Patrick Lorton, CTO and COO, Software & Ops, Schrödinger
Introduction:
This discussion will explore how AI/ML is transforming drug development, highlighting tangible results from Schrödinger and beyond.