Festival of Biologics 2025
Date & Time - September 30th – October 2nd, 2025
Location - Basel, Switzerland
Schrödinger is excited to be participating in the Festival of Biologics 2025 conference taking place on September 30th – October 2nd in Basel, Switzerland. Join us for a presentation by Esam Abualrous, Principal Scientist I at Schrödinger, titled “Advances in Structure-Based Computational Modeling and Collaborative Enterprise Informatics for Biologics.” Stop by booth 501B to speak with Schrödinger scientists.
OCT 1 | 14:40 CET 
Theatre 6 Advances in Structure-Based Computational Modeling and Collaborative Enterprise Informatics for Biologics
Speaker:
Esam Abualrous, Principal Scientist I, Schrödinger
Abstract:
Optimizing biologic drug candidates to enhance favorable traits or minimize liabilities often demands significant experimental effort. This presentation will showcase recent progress in our physics-based, structure-guided computational methods that help accelerate the optimization process. It will cover key challenges in antibody engineering—including predicting antibody-antigen binding affinity, improving structural stability, and addressing developability concerns. This talk will illustrate how these approaches can be integrated within a collaborative informatics platform for biologics discovery, which can merge machine learning (ML) results, experimental data and advanced modeling, execution, and analysis tools to streamline decision-making and centralize essential project information.