Festival of Biologics 2026
Date & Time - October 13th-15th, 2026
Location - Basel, Switzerland
Schrödinger is excited to be participating in the Festival of Biologics 2026 conference taking place on October 13th – 15th in Basel, Switzerland. Join us for a presentation by Esam Abualrous, Principal Scientist, Applications Science at Schrödinger, titled “Accelerating Biologics Design with State-of-the-Art In Silico Modeling and Collaborative Enterprise Informatics.” Stop by booth #292 to speak with Schrödinger scientists.
OCT 14 | 11:50 Accelerating Biologics Design with State-of-the-Art In Silico Modeling and Collaborative Enterprise Informatics
Speaker:
Esam Abualrous
Abstract:
Biologics discovery programs face mounting demands to accelerate timelines while navigating increasing molecular complexity, constrained experimental capacity, and data scattered across modeling and experimental systems. Critical decisions — from variant selection to developability risk assessment and structure-guided optimization — are frequently hampered by siloed workflows and the challenge of reliably bridging computational predictions with experimental outcomes.
In this talk, we will present how physics-based computational modeling (BioLuminate, FEP+) and collaborative enterprise informatics (LiveDesign) can be combined to accelerate modern biologics design. We will walk through an end-to-end workflow spanning early structural assessment, liability and developability analysis, and structure-guided engineering powered by advanced free-energy methods. We will also illustrate how in silico predictions can be integrated with experimental data within LiveDesign to drive iterative design cycles, hypothesis generation, and variant prioritization — enabling faster, more confident biologics discovery and optimization.