Date & Time
- April 23rd, 2026
Location
- Basel, Switzerland
Ligand-Based Screening in the Age of Ultra-Large Chemical Libraries
Dear Scientists,
Readily available chemicals keep increasing rapidly in number while the need for novel chemical matter for drug targets remains at an all time high. Recently, tera-scale virtual libraries have become available enabling trillions of compounds for purchase and deployment in hit discovery projects.
To support the ever-growing access to vast chemical space Schrödinger has developed a plethora of ligand-based tools facilitating efficient and locally-deployable screening campaigns for pharmacophores, ligand shape, and fingerprint methodologies at increasing library sizes, from enumerated to virtual spaces.
We invite you to join us for an interactive, free-of-charge session on Thursday, April 23rd at the Radisson Blu Hotel, Basel. In this extended version of our Lunch & Learn series, Schrödinger scientist will provide an overview of ligand-based tools for different chemical spaces and show the fast turnaround/throughput.
Date & Time:
Thursday, April 23rd, 2026
From 10:00 to 13:30 CET
Program:
+ Welcome Coffee
09:30 – 10:00
+ Presentation on Ligand-based offers at different Chemical Spaces
Tim Knehans, Principal Scientist, Applications Science & Product Management
10:00 – 11:00
Presentation:
- Chemical Spaces: An Overlap Analysis
- Ultra-large Library Screening via QuickShape
- Virtual Space Screenings via Combinatorial Explorer
- Synthesis assessments via Pathfinder & RetroSynth
11:00 – 12:00
Interactive session on Ligand-based tools for Ultra-large libraries
+ Lunch
12:00 – 13:30
+ Discussion & Networking
13:30 – open end
Join us in the afternoon for a Q&A and networking session with our Scientists and Account Managers, providing an opportunity to present your questions and challenges, which the Schrödinger team will endeavor to address.
Register today to secure your seat!
The seminar is free to attend but preregistration is required as seats are limited. Previous-experience with the Schrödinger suite is not required.
Our Speaker
Tim Knehans
Principal Scientist, Applications Science & Product Management, Schrödinger
Tim Knehans joined Schrödinger in 2019 where he works as an Applications Scientist in Europe as well as a Product Manager for Schrödinger’s Cheminformatics Software, overseeing the utilization of ultra-large chemical spaces. Tim obtained his Dr. sc. nat. from the University of Zurich under Amedeo Caflisch before joining professors Didier Rognan & Esther Kellenberger at the University of Strasbourg for a PostDoc. He then joined the Computational Chemistry Department of Merck KGaA working in Drug Discovery & ultra-large libraries as well as a Cheminformatics Team Lead for the SYNTHIA retrosynthesis project.