Join us for the inaugural Schrödinger Medicinal Chemistry Symposium, an event specifically curated for the medicinal chemistry community.

This full-day symposium will highlight the powerful synergy between traditional medicinal chemistry and modern digital workflows.

The program will feature technical presentations and drug discovery case studies from industry leaders, along with a panel discussion and a hands-on workshop.

The event will also include a reception and dedicated networking opportunities. More specific information on the agenda will be added as it becomes available.

Agenda:

Accelerated discovery of a carbamate scaffold Cbl-b inhibitor using generative models and structure-based drug design (Tandem Talk)

• Taylor Quinn, Associate Principal Scientist, Computational Chemistry, AstraZeneca
• Alex Chinn, Senior Scientist, Medicinal Chemistry, AstraZeneca

Tandem Talk

• Derun Li, Executive Director, Nimbus Therapeutics
• Justin Caravella, Senior Director, Computational Chemistry, Nimbus Therapeutics

Structure-based discovery of imidazo[4,5-c]pyridine SARM1 modulators showing paradoxical activation (Tandem Talk)

• Adam Levinson, Director, Medicinal Chemistry, Schrödinger
• Steven Albanese, Research Leader, Computational Chemistry, Schrödinger

Beyond the lead: Medicinal chemistry optimization of potent and platelet-sparing Bcl-xL degraders

• Baljinder Singh, Senior Scientist, Medicinal Chemistry, AstraZeneca

Multi-parameter optimization of p38/MK2 molecular glues: An interactive design challenge (Workshop)

Bridging the gap: Expanding the reach of computational chemistry in drug discovery (Panel)

• Veerabahu Shanmugasundaram, Executive Director, Bristol Myers Squibb
• Additional panelists coming soon

Organizing Committee:

• Melissa Buskes, Senior Scientist, Medicinal Chemistry, Atavistik Bio
• Kevin Cusack, Retired Research Fellow, AbbVie
• Adam Levinson, Director, Medicinal Chemistry, Schrödinger
• Agustina Rodriguez-Granillo, Director, Applications Science, Schrödinger
• Wade Miller, Senior Manager, Education, Schrödinger

Venue:

Bristol Myers Squibb
250 Water Street Cambridge, MA 02141.