Accelerating amorphous solid dispersion (ASD) formulation with Schrödinger’s Materials Science Suite
Date & Time 
Location - Virtual
Amorphous solid dispersions (ASDs) remain an essential strategy for enhancing oral bioavailability of poorly water-soluble drugs. Traditionally, the advanced molecular modeling used to inform formulation design has been exclusively the domain of computational specialists. This webinar will demonstrate how experimental formulators can now actively participate in this process. We will showcase the accessibility of computational screening within Schrödinger’s Materials Science Suite, enabling bench scientists to readily evaluate standard polymer excipients and generate precise, confident lists for laboratory testing.
Divided into a presentation of core capabilities and a practical software walkthrough, this session will demonstrate how to seamlessly integrate computational insights from mixing energies to glass transition temperatures (Tg) into your existing R&D pipeline to reduce experimental iteration and accelerate time-to-market.
Webinar Highlights:
- Democratizing Molecular Modeling
Schrödinger’s Materials Science Suite offers a platform for experimentalists to incorporate computational screening into your formulation workflows without requiring a background in computational chemistry
- The Digital Funnel
A review of the simulation pipeline, moving from rapid compatibility screening (e.g., HPMCAS and copovidone) to detailed physical property predictions (e.g., moisture sorption and Tg)
- Workflow Walkthrough
A step-by-step look at building a polymer-API system using an user-friendly GUI
Our Speakers
Ben Coscia
Principal Scientist II, Materials Science Modeling Services, Schrödinger
Shiva Sekharan
Global Portfolio Leader, Formulations & CSP, Schrödinger
Sivakumar (Shiva) Sekharan, Ph.D., is the Global Portfolio Leader of Formulations and CSP at Schrödinger and is responsible for driving the business development efforts in the formulations space. Before arriving at Schrödinger, Shiva held a business development role at XtalPi Inc., where he led the US solid-state services unit, worked with departmental heads to establish effective goals, sales targets, outlined procedures and best practices and provided strategic directions to increase revenue. Shiva graduated from the University of Duisburg-Essen, Germany with a PhD in Theoretical Chemistry followed by postdoctoral training at the Max-Planck Institute for Polymer Science, Emory University, Fukui Institute for Fundamental Chemistry and Yale University. Shiva is an accomplished computational chemist, with strong research expertise in the areas of solid-state chemistry and drug discovery.