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Melittin Aggregation in Aqueous Solutions: Insight from Molecular Dynamics Simulation

Posted on March 9, 2016January 7, 2025 by Anonymous
Posted in UncategorizedLeave a Comment on Melittin Aggregation in Aqueous Solutions: Insight from Molecular Dynamics Simulation

Optimization of Potent DFG-in Inhibitors of Platelet Derived Growth Factor Receptor’ (PDGF-R’) Guided by Water Thermodynamics

Posted on January 21, 2016January 7, 2025 by Anonymous
Posted in Hit-to-Lead & Lead OptimizationLeave a Comment on Optimization of Potent DFG-in Inhibitors of Platelet Derived Growth Factor Receptor’ (PDGF-R’) Guided by Water Thermodynamics

Water Networks Contribute to Enthalpy/Entropy Compensation in Protein-Ligand Binding

Posted on January 21, 2016January 7, 2025 by Anonymous
Posted in Hit-to-Lead & Lead OptimizationLeave a Comment on Water Networks Contribute to Enthalpy/Entropy Compensation in Protein-Ligand Binding

The role of the active site solvent in the thermodynamics of factor Xa-ligand binding

Posted on January 21, 2016January 7, 2025 by Anonymous
Posted in Hit-to-Lead & Lead OptimizationLeave a Comment on The role of the active site solvent in the thermodynamics of factor Xa-ligand binding

Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1

Posted on December 17, 2015January 7, 2025 by Anonymous
Posted in Structure Prediction & Target EnablementLeave a Comment on Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1

OPLS3: A Force Field Providing Broad Coverage of Drug-like Small Molecules and Proteins

Posted on December 16, 2015January 7, 2025 by Anonymous
Posted in Structure Prediction & Target EnablementLeave a Comment on OPLS3: A Force Field Providing Broad Coverage of Drug-like Small Molecules and Proteins

Chemical Basis for the Recognition of Trimethyllysine by Epigenetic Reader Proteins

Posted on December 15, 2015January 7, 2025 by Anonymous
Posted in Structure Prediction & Target EnablementLeave a Comment on Chemical Basis for the Recognition of Trimethyllysine by Epigenetic Reader Proteins

Estimation of Charge Carrier Mobility in Amorphous Organic Materials Using Percolation Corrected Random-Walk Model

Posted on December 10, 2015January 7, 2025 by Anonymous
Posted in Organic ElectronicsLeave a Comment on Estimation of Charge Carrier Mobility in Amorphous Organic Materials Using Percolation Corrected Random-Walk Model

Accurate Binding Free Energy Predictions in Fragment Optimization

Posted on November 24, 2015January 7, 2025 by Anonymous
Posted in Hit-to-Lead & Lead OptimizationLeave a Comment on Accurate Binding Free Energy Predictions in Fragment Optimization

Electronic Structure of 1 to 2 nm Diameter Silicon Core/Shell Nanocrystals: Surface Chemistry, Optical Spectra, Charge Transfer and Doping

Posted on September 8, 2015January 7, 2025 by Anonymous
Posted in Metals, Alloys & CeramicsLeave a Comment on Electronic Structure of 1 to 2 nm Diameter Silicon Core/Shell Nanocrystals: Surface Chemistry, Optical Spectra, Charge Transfer and Doping

cis-{Pt(NH3)2(L)}2+/+ (L = Cl, H2O, NH3) Binding to Purines and CO: Does π-Back-Donation Play a Role?

Posted on September 8, 2015January 7, 2025 by Anonymous
Posted in Catalysis & ReactivityLeave a Comment on cis-{Pt(NH3)2(L)}2+/+ (L = Cl, H2O, NH3) Binding to Purines and CO: Does π-Back-Donation Play a Role?

Kinetics and thermodynamics of H. transfer from (eta5-C5R5)Cr(CO)3H (R = Ph, Me, H) to methyl methacrylate and styrene

Posted on September 8, 2015January 7, 2025 by Anonymous
Posted in Catalysis & ReactivityLeave a Comment on Kinetics and thermodynamics of H. transfer from (eta5-C5R5)Cr(CO)3H (R = Ph, Me, H) to methyl methacrylate and styrene

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