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Novel Method for Generating Structure-Based Pharmacophores Using Energetic Analysis

Posted on September 8, 2015December 13, 2024 by Anonymous
Posted in UncategorizedLeave a Comment on Novel Method for Generating Structure-Based Pharmacophores Using Energetic Analysis

Closing the side-chain gap in protein loop modeling

Posted on September 8, 2015December 13, 2024 by Anonymous
Posted in UncategorizedLeave a Comment on Closing the side-chain gap in protein loop modeling

Extension of QM/MM docking and its applications to metalloproteins

Posted on September 8, 2015December 13, 2024 by Anonymous
Posted in UncategorizedLeave a Comment on Extension of QM/MM docking and its applications to metalloproteins

Correlation between Performance of QM/MM Docking and Simple Classification of Binding Sites

Posted on September 8, 2015December 13, 2024 by Anonymous
Posted in Informatics and Team CollaborationLeave a Comment on Correlation between Performance of QM/MM Docking and Simple Classification of Binding Sites

Discovery of Novel Fibroblast Growth Factor Receptor 1 Kinase Inhibitors by Structure-Based Virtual Screening

Posted on September 8, 2015December 13, 2024 by Anonymous
Posted in Hit-to-Lead & Lead OptimizationLeave a Comment on Discovery of Novel Fibroblast Growth Factor Receptor 1 Kinase Inhibitors by Structure-Based Virtual Screening

Probing the ‘-Helical Structural Stability of Stapled p53 Peptides: Molecular Dynamics Simulations and Analysis

Posted on September 8, 2015November 28, 2023 by Anonymous
Posted in Structure Prediction & Target EnablementLeave a Comment on Probing the ‘-Helical Structural Stability of Stapled p53 Peptides: Molecular Dynamics Simulations and Analysis

Peroxide-dependent formation of a covalent link between Trp51 and the heme in cytochrome c peroxidase

Posted on September 8, 2015December 13, 2024 by Anonymous
Posted in Informatics and Team CollaborationLeave a Comment on Peroxide-dependent formation of a covalent link between Trp51 and the heme in cytochrome c peroxidase

Quantitative DFT modeling of the enantiomeric excess for dioxirane-catalyzed epoxidations

Posted on September 8, 2015December 13, 2024 by Anonymous
Posted in Catalysis & ReactivityLeave a Comment on Quantitative DFT modeling of the enantiomeric excess for dioxirane-catalyzed epoxidations

Prediction of Absolute Solvation Free Energies using Molecular Dynamics Free Energy Perturbation and the OPLS Force Field

Posted on September 8, 2015December 13, 2024 by Anonymous
Posted in Hit-to-Lead & Lead OptimizationLeave a Comment on Prediction of Absolute Solvation Free Energies using Molecular Dynamics Free Energy Perturbation and the OPLS Force Field

A Role for a Specific Cholesterol Interaction in Stabilizing the Apo Configuration of the Human A2A Adenosine Receptor

Posted on September 8, 2015December 13, 2024 by Anonymous
Posted in UncategorizedLeave a Comment on A Role for a Specific Cholesterol Interaction in Stabilizing the Apo Configuration of the Human A2A Adenosine Receptor

Exploring Structural Variability in X-Ray Crystallographic Models Using Protein Local Optimization by Torsion-Angle Sampling

Posted on September 8, 2015December 13, 2024 by Anonymous
Posted in UncategorizedLeave a Comment on Exploring Structural Variability in X-Ray Crystallographic Models Using Protein Local Optimization by Torsion-Angle Sampling

Computational Approaches for Fragment-Based and De Novo Design

Posted on September 8, 2015December 13, 2024 by Anonymous
Posted in UncategorizedLeave a Comment on Computational Approaches for Fragment-Based and De Novo Design

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