EMPOWER

Transform drug discovery and materials research with advanced molecular modeling.

Pushing the limits of possible

Our physics-based computational platform integrates differentiated solutions for predictive modeling, data analytics, and collaboration to enable rapid exploration of chemical space.
 
Our platform is deployed by industry leaders worldwide for drug discovery, as well as for materials science in fields as diverse as aerospace, energy, semiconductors, and electronics displays. The platform powers our own drug discovery efforts, from target identification to hit discovery to lead optimization. It also drives our research collaborations to develop novel medicines for critical public health needs.
 
With more than 150 Ph.D. scientists on our team, we invest heavily in R&D. We’ve published over 400 peer-reviewed papers that demonstrate the strength of our physics-based approaches, and we’re continually pushing the limits of computer modeling.

 

CUTTING THROUGH THE VASTNESS OF CHEMICAL SPACE

Traditional pharma approaches to drug discovery synthesize  ~1,000 compounds a year.

Our physics-based platform evaluates billions of molecules per week with a high degree of accuracy.

Our approach enables discovery of high-quality, novel molecules more rapidly, at lower cost, and we believe with a higher likelihood of success compared to traditional methods.

OUR PLATFORM OPENS NEW WORLDS OF POSSIBILITY.

Find the solutions you’re looking for:

DRUG DISCOVERY

Comprehensive solutions to accelerate lead discovery and optimization, validated by our collaborators' success across a wide array of targets.

MATERIALS SCIENCE

Molecular simulations of chemical systems to design materials essential to modern life.

Materials Science

SOLUTION SPOTLIGHT:

LIVEDESIGN 

LiveDesign, a linchpin of our platform, enables interactive and collaborative molecule design, aggregation and sharing of data, and end-to-end discovery project coordination between chemists, modelers, and biologists. Learn more about our user-friendly enterprise informatics solution.

REQUEST INFO

Our platform is used by industry leaders globally. See how our physics-based methods can help you open new worlds of possibility.

ACADEMIC LICENSING

We support the next generation of scientists through special licensing for academic institutions.

Biologics Drug Discovery Products

Materials Science Products

J. Med. Chem. 2017, 60, 6, 2485-2497)
J. Med. Chem. 2017, 60, 6, 2485-2497)

THE POWER OF THE SCHRÖDINGER PLATFORM

The power of our platform can be seen in a case study published in 2017 in the Journal of Medicinal Chemistry.  

Researchers compared the effectiveness of four approaches to identify the 10 compounds most likely to yield tight binding with a target protein: selection by a medicinal chemist, manual modeling, docking followed by manual filtering, and free energy calculations (FEP) using the Schrödinger platform. Researchers then synthesized the molecules recommended by each approach. 

The Schrödinger FEP approach outperformed the others; 80 percent of its recommended molecules demonstrated improved affinity, compared with 10 percent of molecules suggested by the other approaches.
 

TRAINING AND SUPPORT

We have a world-class support organization ready to help you, whether you have a technical question or need a scientific consultation. Our dedicated education team has developed a host of training material available online. Our team is also available for customized training.

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