Long-range electrostatic complementarity governs substrate recognition by human chymotrypsin C, a key regulator of digestive enzyme activation Posted on September 8, 2015December 13, 2024 by Anonymous
Development and Characterization of Nonpeptidic Small Molecule Inhibitors of the XIAP/Caspase-3 Interaction Posted on September 8, 2015December 13, 2024 by Anonymous
The dual functions of the extreme N-terminus of TDP-43 in regulating its biological activity and inclusion formation Posted on September 8, 2015December 13, 2024 by Anonymous
Synthesis and Discovery of Macrocyclic Polyoxygenated Bis-7-azaindolylmaleimides as a Novel Series of Potent and Highly Selective Glycogen Synthase Kinase-3 Inhibitors Posted on September 8, 2015December 13, 2024 by Anonymous
Virtual screening of electron acceptor materials for organic photovoltaic applications Posted on September 8, 2015December 13, 2024 by Anonymous
Synthesis and SAR of Thrombin Inhibitors Incorporating a Novel 4-Amino-Morpholinone Scaffold: Analysis of X-ray Crystal Structure of Enzyme Inhibitor Complex Posted on September 8, 2015December 13, 2024 by Anonymous
Lead optimization mapper: Automating free energy calculations for lead optimization Posted on September 8, 2015December 13, 2024 by Anonymous
Design, Synthesis, and Pharmacology of a Highly Subtype-Selective GluR1/2 Agonist, (RS)-2-Amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic Acid (Cl-HIBO) Posted on September 8, 2015December 13, 2024 by Anonymous
Applying physics-based scoring to calculate free energies of binding for single amino acid mutations in protein-protein complexes Posted on September 8, 2015December 13, 2024 by Anonymous
(S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl) propionic Acid, a Potent and Selective Agonist at the GluR5 Subtype of Ionotropic Glutamate Receptors. Synthesis, Modeling, and Molecular Pharmacology Posted on September 8, 2015December 13, 2024 by Anonymous
Synthesis, biological evaluation, hydration site thermodynamics, and chemical reactivity analysis of ‘-keto substituted peptidomimetics for the inhibition of Plasmodium falciparum Posted on September 8, 2015December 13, 2024 by Anonymous
Synthesis of Novel Thrombin Inhibitors. Use of Ring-Closing Metathesis Reactions for Synthesis of P2 Cyclopentene- and Cyclohexenedicarboxylic Acid Derivatives Posted on September 8, 2015December 13, 2024 by Anonymous