The landscape of protein engineering is evolving rapidly, driven by cutting-edge computational techniques that are transforming biopharmaceutical discovery and optimization. Together, we will explore groundbreaking methods that enable accurate modeling of critical physical endpoints, including thermal stability, protein-protein binding affinity, and pH sensing profiles. These innovations promise to accelerate early-stage discovery while enhancing the precision of biotherapeutic design.

In this webinar, we will introduce Schrödinger’s FEP+ Residue Scan, a next-generation tool that achieves approximately 15x speedup compared to traditional Protein FEP methods, without significant loss of accuracy. This capability enables researchers to perform large-scale residue perturbation studies with high efficiency and reliability.

We will also present a practical example of computational antibody optimization, showcasing how these tools can be applied to real-world challenges. Additionally, we will discuss how Schrödinger’s biologics services can further streamline and customize workflows, empowering scientists to tackle complex projects effectively. Join us to discover how these next-generation solutions are transforming the field of protein engineering and driving impactful innovation in the biopharmaceutical industry.

Webinar Highlights

• Overview of Schrödinger’s biologics capabilities and offerings for rational antibody design
• Key features of FEP+ Residue Scan and Protein FEP+ for protein mutational engineering
• Introduction to Schrödinger’s biologics services to lower the barrier to entry for modeling novices