MS Complex Bilayer Builder

Automatically build realistic membranes with embedded proteins
MS Complex Bilayer Builder

Overview

MS Complex Bilayer Builder streamlines system preparation and accelerates your research with automated workflows that build complex, biologically-realistic lipid bilayers with embedded proteins, ready for further molecular dynamics simulations.

background pattern

Benefits

Fast, reliable membrane-protein system construction

Generate lipid bilayers with and without embedded proteins in biologically-realistic environments using automated protocols that minimize setup errors and significantly reduce preparation time

Flexible, customizable workflows

Support a wide range of lipid types, protein orientations, and membrane compositions to suit various biological scenarios and research needs

Cross-platform capability

Seamlessly integrate with multiple simulation engines, ensuring adaptability and reproducibility across diverse computational setups

Broad applications across materials science and life science research areas

Structure Prediction and Target Enablement

Consumer Packaged Goods

Pharmaceutical Formulations & Delivery

Documentation & Tutorials

Get answers to common questions and learn best practices for using Schrödinger’s software.

Materials Science Tutorial

Building and Analyzing a Complex Lipid Bilayer and Embedding a Membrane Protein

Learn to build and analyze a complex lipid bilayer and how to embedd a protein.

Materials Science Documentation

Complex Bilayer Builder Panel

Build single or multi-component lipid membranes with or without an embedded membrane protein.

Materials Science Documentation

Membrane Analysis Panel

Calculate structural properties for a lipid membrane over the selected frames of a trajectory.

Materials Science Documentation

Membrane Analysis Viewer Panel

View plots of the structural properties of a lipid over the course of a molecular dynamics trajectory, generated using the Membrane Analysis panel.

Related Products

Desmond

High-performance molecular dynamics (MD) engine providing high scalability, throughput, and scientific accuracy

MS CG

Efficient coarse-grained (CG) molecular dynamics (MD) simulations for large systems over long time scales

FEP+

High-performance free energy calculations for drug discovery

OPLS4

Modern, comprehensive force field for accurate molecular simulations

Contract Research Services

Advance your materials R&D with unrivaled technologies and expertise

Training & Resources

Online certification courses

Level up your skill set with hands-on, online molecular modeling courses. These self-paced courses cover a range of scientific topics and include access to Schrödinger software and support.

Tutorials

Learn how to deploy the technology and best practices of Schrödinger software for your project success. Find training resources, tutorials, quick start guides, videos, and more.